Wild type Cre mRNA encodes for the Cre recombinase enzyme, a site-specific DNA recombinase derived from bacteriophage P1. When delivered into cells expressing loxP-flanked DNA sequences, Cre mRNA enables precise genetic modifications including gene knockout, insertion, or chromosomal rearrangements. Due to its high transfection efficiency, transient expression profile and compatibility with diverse delivery systems, Cre mRNA serves as a gold-standard tool for conditional genome editing and is indispensable for developmental biology, cancer research, and translational medicine.
• Sequence optimized and selected for high expression.
• Oligo-dT purification ensures high quality and purity.
• Carefully controlled processes to minimize batch-to-batch variation.
1330 nt
2 mg/mL
1 mM sodium citrate, pH 6.5
Below -65℃
Dry ice
Visual
USP<791>
UV
UV
HPLC
CE
LC-MS
LC-MS
Nano Orange
ELISA
qPCR
Gel-clot method