Wild type Cas9 mRNA (N1-Me-Pseudo UTP) allows for the expression of a Streptococcus pyogenes SF370 Cas9 protein (CRISPR-associated protein 9), which is part of the CRISPR genome editing system, when transfected into cells. In the CRISPR system, when co-transfected with guide RNA (gRNA) targeting specific genomic loci, the Cas9 protein can cleave the targeted genes under the guidance of the gRNA.

• Used for CRISPR/Cas9-mediated gene editing.

• Sequence optimized and selected for high expression.

• Oligo-dT purification ensures high quality and purity.

• Carefully controlled processes to minimize batch-to-batch variation.